Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493049 | 0.84 | NPC1 (0.44) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL28489346 | 0.80 | CACNA1F (0.41) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL28902448 | 0.74 | KMT2A (0.53) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL10434032 | 0.74 | NPC1 (0.46) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL7055470 | 0.73 | MAPT (0.44) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL21066864 | 0.72 | KMT2A (0.45) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL5724096 | 0.71 | MAPT (0.49) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL28482764 | 0.70 | MAPT (0.43) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL28486014 | 0.70 | ALDH1A1 (0.43) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL28811902 | 0.70 | SLC6A3 (0.50) | KMT2AMAPTMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651286-B | High-selectivity synthesis method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2020-08-11 | — | — | CN | disclosed |