Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 3/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493091 | 0.83 | JAK2 (0.43) | JAK2JAK3JAK1TYK2GRM5 | |
| SCHEMBL28709275 | 0.82 | — | — | |
| SCHEMBL22574125 | 0.75 | TSHR (0.50) | JAK2JAK1TYK2TSHRGRM5 | |
| SCHEMBL23770974 | 0.74 | MEN1 (0.47) | TSHR | |
| SCHEMBL4642968 | 0.71 | ROCK2 (0.48) | SIRT2LMNANPC1PKMRAB9A | |
| SCHEMBL23771038 | 0.71 | NAMPT (0.48) | TSHRGRM5LMNANPC1PKM | |
| SCHEMBL9572445 | 0.71 | KMT2A (0.58) | SIRT2SIRT1SIRT3 | |
| SCHEMBL23501633 | 0.70 | MKNK1 (0.43) | — | |
| SCHEMBL31359358 | 0.70 | MKNK1 (0.43) | — | |
| SCHEMBL28721656 | 0.69 | RAB9A (0.71) | GRM5LMNANPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936484-A | Chromenopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase | 拉文纳制药公司 | 2020-11-13 | — | — | CN | disclosed |