Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956331 | 0.79 | ASPH (0.36) | ASPH | |
| SCHEMBL29953210 | 0.79 | ASPH (0.36) | ASPH | |
| SCHEMBL29953406 | 0.78 | PIK3CD (0.38) | PIK3R1PIK3CAASPHAKR1C3PIK3CD | |
| SCHEMBL2554225 | 0.76 | CNR2 (0.32) | CNR2 | |
| SCHEMBL3840400 | 0.76 | PIK3R1 (0.42) | PIK3R1PIK3CAASPHKCNQ3KCNQ2 | |
| SCHEMBL16115971 | 0.75 | MEN1 (0.41) | GAA | |
| SCHEMBL29954959 | 0.75 | KCNQ3 (0.33) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL30503537 | 0.75 | PIK3R1 (0.36) | PIK3R1PIK3CAASPHKCNQ3KCNQ2 | |
| SCHEMBL432680 | 0.75 | PIK3R1 (0.36) | PIK3R1PIK3CAASPHKCNQ3KCNQ2 | |
| SCHEMBL29395367 | 0.75 | PIK3R1 (0.36) | PIK3R1PIK3CAASPHKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995587-A | 1, 4-disubstituted 3, 4-dihydro-2 (3H) -quinazolinone compound and synthetic method and application thereof | 上海工程技术大学 | 2020-11-27 | — | — | CN | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-111995587-B | 1, 4-disubstituted 3, 4-dihydro-2 (3H) -quinazolinone compound and synthesis method and application thereof | 上海工程技术大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-111995587-A | 1, 4-disubstituted 3, 4-dihydro-2 (3H) -quinazolinone compound and synthetic method and application thereof | 上海工程技术大学 | 2020-11-27 | — | — | CN | disclosed |