SCHEMBL284862

SCHEMBL284862

CC(=O)OC(=O)CCCCCN

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 4/20 0.58
LMNA P02545 4/20 0.48
ALDH1A1 P00352 3/20 0.48
THRB P10828 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
PLG P00747 1/20 0.48
ALOX15 P16050 1/20 0.48
SLC6A2 P23975 1/20 0.48
RECQL P46063 1/20 0.48
SLC6A3 Q01959 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 1/20 0.44
NFKB1 P19838 1/20 0.44
BLM P54132 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
PTGS1 P23219 1/20 0.40
TSHR P16473 3/20 0.38
DGKA P23743 1/20 0.38
GABRR3 A8MPY1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19816433 1.00 PAOX (0.58) PAOXLMNAALDH1A1THRBKMT2A
SCHEMBL9170595 1.00 PAOX (0.58) PAOXLMNAALDH1A1THRBKMT2A
Hexadecylamine SCHEMBL28285653 0.92 PAOX (0.50) PAOXLMNAALDH1A1KMT2AMEN1
SCHEMBL5813282 0.91 CYP1A2 (0.56) PAOXLMNAALDH1A1THRBKMT2A
SCHEMBL17433647 0.89 CYP1A2 (0.54) PAOXLMNAALDH1A1THRBKMT2A
SCHEMBL12538257 0.89 CYP1A2 (0.54) PAOXLMNAALDH1A1THRBKMT2A
SCHEMBL1539265 0.89 ALDH1A1 (0.47) PAOXLMNAALDH1A1PTGS1TSHR
SCHEMBL7845680 0.89 ALDH1A1 (0.47) PAOXLMNAALDH1A1PTGS1TSHR
SCHEMBL1539244 0.89 ALDH1A1 (0.47) PAOXLMNAALDH1A1PTGS1TSHR
SCHEMBL28687285 0.89 ALDH1A1 (0.47) PAOXLMNAALDH1A1PTGS1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity GENOMATICA, INC. (US) 2026-03-17 US disclosed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 US disclosed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 US disclosed
US-20250305013-A1 Methods and Compositions for Making Amide Compounds GENOMATICA, INC. (US) 2025-10-02 US disclosed
US-20240294885-A1 ENGINEERED ENZYMES AND METHODS OF MAKING AND USING AGAIN BIO APS (DK) 2024-09-05 US disclosed
EP-4423259-A1 ENGINEERED ENZYMES AND METHODS OF MAKING AND USING Genomatica, Inc. (US) 2024-09-04 EP disclosed
CN-118339281-A Engineered enzymes and methods of making and using the same 基因组股份公司 2024-07-12 CN disclosed
US-20240182935-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2024-06-06 US disclosed
US-11834690-B2 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid GENOMATICA, INC. (US) 2023-12-05 US disclosed
EP-4277976-A1 METHODS AND COMPOSITIONS FOR MAKING AMIDE COMPOUNDS Genomatica, Inc. (US) 2023-11-22 EP disclosed
WO-2014099725-A1 MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING ADIPATE, 6-AMINOCAPROATE, HEXAMETHYLENEDIAMINE OR CAPROLACTAM RELATED THERETO GENOMATICA, INC. (US) 2014-06-26 WO disclosed
US-8753850-B2 2014-06-17 US disclosed
US-20130303723-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2013-11-14 US disclosed
US-8377680-B2 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid GENOMATICA, INC. (US) 2013-02-19 US disclosed
WO-2012177721-A1 MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-12-27 WO disclosed
US-20120282661-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-11-08 US disclosed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 EP disclosed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 US disclosed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 WO disclosed
CN-86107574-A Compositions containing penem or carbapenem antibiotics and their use 1987-05-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity ACADM, ALDH7A1, ADSL PAOX 471/4885LMNA 3078/4885ALDH1A1 50/4885
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 PAOX 1178/4885LMNA 2536/4885ALDH1A1 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.