Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 8/20 | 0.83 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.83 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.83 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.83 |
| ▸ | GCGR | P47871 | 5/20 | 0.83 |
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | RAF1 | P04049 | 4/20 | 0.83 |
| ▸ | TP53 | P04637 | 3/20 | 0.83 |
| ▸ | BRAF | P15056 | 2/20 | 0.83 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.75 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.68 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.66 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CIT | O14578 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12561713 | 1.00 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL18292488 | 0.98 | MAPK13 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL15401173 | 0.98 | MAPK13 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL5307418 | 0.98 | MAPK13 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL252964 | 0.98 | MAPK13 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL9619859 | 0.98 | MAPK13 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL8010209 | 0.91 | NOX1 (0.76) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL16667652 | 0.91 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL28486758 | 0.91 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL12561692 | 0.91 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024196958-A2 | COMPOUNDS FOR RESTORING SUSCEPTIBILITY TO BETA-LACTAM ANTIBIOTICS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2024-09-26 | — | — | WO | disclosed |