Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841217 | 0.81 | CRHBP (0.44) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28487774 | 0.80 | MEN1 (0.50) | AKR1C2AKR1C1GRM1MEN1CYP1A2 | |
| SCHEMBL28494909 | 0.80 | FFAR1 (0.51) | AKR1C4AKR1C3AKR1C2AKR1C1GRM1 | |
| SCHEMBL11844019 | 0.80 | CRHBP (0.43) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28494831 | 0.80 | GRM1 (0.61) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL11516331 | 0.79 | GRM1 (0.46) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL25240807 | 0.78 | IDO1 (0.43) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL1439143 | 0.78 | IDO1 (0.43) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL29890267 | 0.78 | IDO1 (0.43) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL28487773 | 0.76 | DHFR (0.46) | GRM1MEN1CYP1A2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848430-B | Synthetic method of 2- ([ 1,1' -biphenyl ] -4-yl) -2-glycine compound | 马鞍山诺恩特医药科技有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-111848430-A | Synthesis method of 2- ([1,1' -biphenyl ] -4-yl) -2-glycine compound | 苏州爱玛特生物科技有限公司 | 2020-10-30 | — | — | CN | disclosed |