SCHEMBL28487252

SCHEMBL28487252

Cc1cncc(O[Si](C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
CHRNB3 Q05901 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
CYP2A6 P11509 3/20 0.33
GCK P35557 5/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
CYP3A4 P08684 1/20 0.31
PPARG P37231 1/20 0.31
S1PR1 P21453 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1B1 Q16678 1/20 0.30
VEGFA P15692 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91463 0.76
SCHEMBL29465753 0.76
SCHEMBL11415062 0.75 ALDH1A1 (0.42) CYP3A4
SCHEMBL2461839 0.75 ALDH1A1 (0.37) CYP3A4
SCHEMBL768929 0.73 ATM (0.38) ATMCHRNB1CHRNB2CHRNB4CHRNA3
SCHEMBL12695010 0.71 CHRNB2 (0.44) ATMCHRNB1CHRNB2CHRNB4CHRNA3
SCHEMBL14805691 0.71 CHRNB1 (0.37) ATMCHRNB1CHRNB2CHRNB4CHRNA3
SCHEMBL15664521 0.71
SCHEMBL10061804 0.71 CHRNB2 (0.47) CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL24225 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111983111-B Method for measuring retention rate of cigarette filter stick on hydroxypyridine 贵州中烟工业有限责任公司 2022-10-14 CN disclosed
CN-111983111-A Method for measuring retention rate of cigarette filter stick on hydroxypyridine 贵州中烟工业有限责任公司 2020-11-24 CN disclosed