Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.43 |
| ▸ | PYGL | P06737 | 3/20 | 0.43 |
| ▸ | PYGM | P11217 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512434 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2397483 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7759963 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2848751 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7759960 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL3459496 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL28509349 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL6908836 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL3459494 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| Acetic Acid SCHEMBL30370283 | 0.89 | PYGB (0.42) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991557-B1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | OE OPERATIONS (FR) | 2010-01-20 | — | — | EP | claimed |
| US-20090054353-A1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-02-26 | — | — | US | claimed |
| EP-1991557-A1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | OE Operations (FR) | 2008-11-19 | — | — | EP | claimed |
| WO-2007096532-A1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | OE OPERATIONS (FR) | 2007-08-30 | — | — | WO | claimed |
| EP-1991557-B1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | OE OPERATIONS (FR) | 2010-01-20 | — | — | EP | disclosed |
| US-20090054353-A1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-02-26 | — | — | US | disclosed |
| EP-1991557-A1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | OE Operations (FR) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007096532-A1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | OE OPERATIONS (FR) | 2007-08-30 | — | — | WO | disclosed |
| US-6294521-B1 | SUGAR PHOSPHATES | AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2001-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054353-A1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | MAN2A1, MAN2B1, MANBA | PYGB 268/4885PYGL 92/4885PYGM 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.