Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.37 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | PYGM | P11217 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908836 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL3459496 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL28509349 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2397483 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2848751 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7759963 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL6512434 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7759960 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2848748 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| Acetic Acid SCHEMBL30370283 | 0.83 | PYGB (0.42) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029574-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF GEMCITABINE AND ITS INTERMEDIATES USING NOVEL PROTECTING GROUPS AND ION EXCHANGE RESINS | KANNAN VISHWANATH (IN) | 2010-03-18 | — | — | WO | disclosed |
| CN-101296934-A | Process for preparing gemcitabine and associated intermediates | CHEMAGIS LTD (IL) | 2008-10-29 | — | — | CN | disclosed |
| EP-1931693-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007027564-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-03-08 | — | — | WO | disclosed |