Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.43 |
| ▸ | PYGL | P06737 | 3/20 | 0.43 |
| ▸ | PYGM | P11217 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512434 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2848748 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7759963 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2848751 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL7759960 | 1.00 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL3459496 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL28509349 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL6908836 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL3459494 | 0.93 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| Acetic Acid SCHEMBL30370283 | 0.89 | PYGB (0.42) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109172586-A | It is a kind of for alleviating the composition of skin irritatin | 福州百草堂医药科技有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-114591313-A | Preparation method of canagliflozin | 南京圣鼎医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |
| US-9359322-B2 | C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and methods of using the same to inhibit neoplastic cell growth | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-06-07 | — | — | US | disclosed |
| US-8026220-B2 | C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-09-27 | — | — | US | disclosed |
| US-20110212906-A1 | C-LINKED GLUCURONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHODS OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION | 2011-09-01 | — | — | US | disclosed |
| US-20090215706-A1 | C-LINKED GLUCURONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHOD OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION | 2009-08-27 | — | — | US | disclosed |
| US-7528114-B2 | C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-05 | — | — | US | disclosed |
| EP-1891085-A2 | C-LINKED GLUCORONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHOD OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-27 | — | — | EP | disclosed |
| US-20060287255-A1 | C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION | 2006-12-21 | — | — | US | disclosed |
| WO-2006119402-A2 | C-LINKED GLUCORONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHOD OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-11-09 | — | — | WO | disclosed |
| US-6930180-B2 | Chemically modified proteins with a carbohydrate moiety | GENENCOR INTERNATIONAL, INC. (US) | 2005-08-16 | — | — | US | disclosed |
| US-6294521-B1 | SUGAR PHOSPHATES | AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2001-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287255-A1 | C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth | UGT2B17, ALDH1A2, UGT2B7 | PYGB 987/4885PYGL 203/4885PYGM 2034/4885 |
| US-20110212906-A1 | C-LINKED GLUCURONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHODS OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH | ALDH1A2, UGT2B17, UGT2B7 | PYGB 975/4885PYGL 172/4885PYGM 2136/4885 |
| US-20090215706-A1 | C-LINKED GLUCURONIDE OF N-(4-HYDROXYBENZYL) RETINONE, ANALOGS THEREOF, AND METHOD OF USING THE SAME TO INHIBIT NEOPLASTIC CELL GROWTH | UGT2B17, ALDH1A2, UGT2B7 | PYGB 987/4885PYGL 203/4885PYGM 2034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.