Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806062 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL28490652 | 0.81 | L3MBTL1 (0.46) | MAPTALDH1A1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL6680576 | 0.81 | MAPT (0.49) | MAPTALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL9392854 | 0.81 | ALDH1A1 (0.62) | MAPTALDH1A1ASAH2HDAC3HDAC1 | |
| SCHEMBL10608761 | 0.81 | MAPT (0.49) | MAPTALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL28807512 | 0.80 | MAPT (0.47) | MAPTALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL8667678 | 0.80 | MAPT (0.47) | MAPTALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL17294442 | 0.77 | CYP19A1 (0.51) | MAPTALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL6683966 | 0.77 | MAPT (0.47) | MAPTALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL10607510 | 0.77 | MAPT (0.47) | MAPTALDH1A1CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088151-A | Process for producing fluoromethyl derivative | 大金工业株式会社 | 2020-12-15 | — | — | CN | disclosed |