Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928087 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL28488450 | 0.82 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL9026246 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL16806060 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL173199 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL11712010 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL16806066 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL5712846 | 0.78 | HSD17B10 (0.52) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL11431941 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 | |
| SCHEMBL5025416 | 0.77 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086495-A1 | PROCESS FOR THE PREPARATION OF CHIRAL 2-ARYL MORPHOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-06-18 | — | — | WO | disclosed |