Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462647 | 0.87 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2HTTTAS1R3 | |
| SCHEMBL6113261 | 0.87 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2HTTTAS1R3 | |
| SCHEMBL1107151 | 0.81 | MEN1 (0.60) | KMT2AMEN1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL29668381 | 0.81 | MEN1 (0.60) | KMT2AMEN1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL124710 | 0.79 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2HTTTAS1R3 | |
| SCHEMBL7634150 | 0.78 | SMN1; SMN2 (0.44) | KMT2AMEN1SMN1; SMN2HTTTAS1R3 | |
| SCHEMBL8948919 | 0.78 | TSHR (0.52) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL19256975 | 0.78 | TAS1R3 (0.48) | KMT2AMEN1SMN1; SMN2HTTTAS1R3 | |
| SCHEMBL9579673 | 0.77 | ALDH1A1 (0.58) | KMT2AMEN1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL30409908 | 0.77 | NPC1 (0.47) | KMT2AMEN1SMN1; SMN2HTTTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111807977-A | 9-aniline fluorene-9-carboxylic ester compound and preparation method thereof | 武汉理工大学 | 2020-10-23 | — | — | CN | disclosed |