Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353105 | 1.00 | TNFRSF1A (0.53) | TNFRSF1AAKR1C1AKR1C3GABBR2GABBR1 | |
| SCHEMBL11306201 | 0.92 | TNFRSF1A (0.61) | TNFRSF1AAKR1C1AKR1C3GABBR2GABBR1 | |
| 1,6-Hexanediol SCHEMBL9720404 | 0.89 | TNFRSF1A (0.52) | TNFRSF1AAKR1C1AKR1C3GABBR2GABBR1 | |
| SCHEMBL2848863 | 0.80 | TNFRSF1A (0.51) | TNFRSF1AAKR1C1GABBR2GABBR1MEN1 | |
| SCHEMBL11510057 | 0.76 | GLRA3 (0.52) | TNFRSF1AGABBR2GABBR1MEN1KMT2A | |
| SCHEMBL10705030 | 0.76 | GLRA3 (0.52) | TNFRSF1AGABBR2GABBR1MEN1KMT2A | |
| SCHEMBL11307029 | 0.75 | CYP3A4 (0.60) | TNFRSF1AAKR1C3GABBR2GABBR1MEN1 | |
| SCHEMBL11300871 | 0.74 | GABBR2 (0.51) | TNFRSF1AGABBR2GABBR1MEN1KMT2A | |
| SCHEMBL11300882 | 0.74 | GABBR2 (0.51) | TNFRSF1AGABBR2GABBR1MEN1KMT2A | |
| SCHEMBL2516211 | 0.74 | LMNA (0.46) | TNFRSF1AGABBR2GABBR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100040806-A1 | CELLULOSE ESTER OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE CELLULOSE ESTER OPTICAL FILM, AND METHOD FOR PRODUCING CELLULOSE ESTER OPTICAL FILM | KONICA MINOLTA OPTO, INC. (JP) | 2010-02-18 | — | — | US | disclosed |