Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281248 | 0.79 | CYP11B2 (0.54) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL28482762 | 0.77 | CYP11B2 (0.49) | CYP11B2MEN1KMT2A | |
| SCHEMBL21001234 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDNPC1MAPTSMN1; SMN2 | |
| SCHEMBL22573887 | 0.76 | CYP11B2 (0.50) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL30919616 | 0.76 | CYP11B2 (0.50) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL30281205 | 0.76 | ALDH1A1 (0.61) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL21816208 | 0.76 | ALDH1A1 (0.61) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL3377698 | 0.72 | NPC1 (0.57) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL31745141 | 0.72 | CYP11B2 (0.47) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL20153317 | 0.72 | LMNA (0.48) | CYP11B2ALDH1A1HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936484-A | Chromenopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase | 拉文纳制药公司 | 2020-11-13 | — | — | CN | disclosed |