SCHEMBL284889

SCHEMBL284889

ClC(Cl)=C(Cl)c1cccc(Cl)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
P2RX7 Q99572 3/20 0.43
JAK2 O60674 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
TAS1R2 Q8TE23 1/20 0.41
ALDH1A1 P00352 4/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
PNMT P11086 1/20 0.38
PKM P14618 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10438862 0.94 TSHR (0.50) TSHRERCC5FEN1P2RX7JAK2
SCHEMBL28913078 0.82 TSHR (0.52) TSHRERCC5FEN1P2RX7JAK2
SCHEMBL6429349 0.81 TSHR (0.43) TSHRERCC5FEN1P2RX7ALDH1A1
SCHEMBL251174 0.80 CES2 (0.54) TSHRERCC5FEN1ALDH1A1CES2
SCHEMBL2130360 0.80 TSHR (0.60) TSHRERCC5FEN1P2RX7JAK2
SCHEMBL11729147 0.79 TSHR (0.53) TSHRERCC5FEN1P2RX7ALDH1A1
SCHEMBL11859876 0.77 TSHR (0.52) TSHRERCC5FEN1P2RX7JAK2
SCHEMBL21630687 0.76 TSHR (0.56) TSHRERCC5FEN1P2RX7JAK2
SCHEMBL93365 0.76 TSHR (0.68) TSHRERCC5FEN1P2RX7JAK2
SCHEMBL27379658 0.76 TSHR (0.56) TSHRERCC5FEN1P2RX7JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355043-A Rubber-reinforced vinylaromatic (co) polymers and process for their preparation 维尔萨利斯股份公司 2024-07-16 CN claimed
WO-2023105386-A1 RUBBER-REINFORCED VINYLAROMATIC (CO)POLYMERS AND PROCESS FOR THE PREPARATION THEREOF VERSALIS S.P.A. (IT) 2023-06-15 WO claimed
EP-2999723-B1 CATIONIC POLYMERIZATION PROCESS FOR THE SYNTHESIS OF NANO-STRUCTURED POLYMERS CONTAINING GRAPHENE VERSALIS SPA (IT) 2018-10-17 EP claimed
CN-105246927-B Cationic polymerization process for synthesizing the nanostructured polymers comprising graphene 维尔萨利斯股份公司 2017-10-17 CN claimed
US-9493594-B2 Cationic polymerization process for the synthesis of nano-structured polymers containing graphene VERSALIS S.P.A. (IT) 2016-11-15 US claimed
US-20160152748-A1 Cationic Polymerization Process For The Synthesis Of Nano-Structured Polymers Containing Graphene VERSALIS SPA (IT) 2016-06-02 US claimed
EP-2999723-A1 CATIONIC POLYMERIZATION PROCESS FOR THE SYNTHESIS OF NANO-STRUCTURED POLYMERS CONTAINING GRAPHENE Versalis S.p.A (IT) 2016-03-30 EP claimed
US-7608669-B2 Preparation of impact-resistant thermoplastic materials on the basis of styrene/butadiene copolymers with polydisperse blocks DYNASOL ELASTOMEROS, S.A. DE C.V. (MX) 2009-10-27 US claimed
US-7504446-B2 Aqueous inks containing colored polymers XEROX CORPORATION (US) 2009-03-17 US claimed
US-20060194915-A1 Preparation of impact-resistant thermoplastic meterials on the basis of stryrene/butadiene copolymers with polydisperse blocks MORALES-BALADO GRACIELA 2006-08-31 US claimed
US-20060074142-A1 Aqueous inks containing colored polymers XEROX CORPORATION 2006-04-06 US claimed
EP-1574535-A1 PREPARATION OF IMPACT-RESISTANT THERMOPLASTIC MATERIALS ON THE BASIS OF STRYRENE/BUTADIENE COPOLYMERS WITH POLYDISPERSE BLOCKS Dynasol Elastomeros, S.A. De C.V. (MX) 2005-09-14 EP claimed
US-5698361-A DIAZONIUM COMPOUND, POLYMERIC BINDER; DURABILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-12-16 US claimed
EP-0270865-B1 LOW HAZE TRANSPARENT COMPOSITIONS AND PROCESS FOR PREPARING THEM ELF ATOCHEM ITALIA S.r.l. (IT) 1993-08-25 EP claimed
US-5183851-A Thermoplastic resin ELF ATOCHEM ITALIA S.R.L. (IT) 1993-02-02 US claimed
EP-0218252-B1 MULTILAYER COEXTRUDED POLYMER SLABS AND STRUCTURAL SHAPES AND PROCESS FOR THEIR PRODUCTION ECP ENICHEM POLIMERI S.r.l. (IT) 1991-12-27 EP claimed
US-4868058-A COEXTRUSION WITHOUT ADHESIVE MONTEDIPE S.P.A. (IT) 1989-09-19 US claimed
EP-0270865-A2 Low haze transparent compositions and process for preparing them ELF ATOCHEM ITALIA S.r.l. (IT) 1988-06-15 EP claimed
EP-0218252-A2 Multilayer coextruded polymer slabs and structural shapes and process for their production ECP ENICHEM POLIMERI S.r.l. (IT) 1987-04-15 EP claimed
US-4423089-A LATEX COPOLYMER CONSISTING OF DIOLEFIN, MONOVINYL MONOMER, AND POLYVINYL OR ACRYOYL MONOMER FUJI PHOTO FILM CO., LTD. (JP) 1983-12-27 US claimed