SCHEMBL93365

SCHEMBL93365

O=C(Cl)c1cccc(Cl)c1Cl

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
ALDH1A1 P00352 5/20 0.56
ERCC5 P28715 1/20 0.53
FEN1 P39748 1/20 0.53
P2RX7 Q99572 3/20 0.52
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
JAK2 O60674 1/20 0.49
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
TAS1R2 Q8TE23 1/20 0.49
ALOX15 P16050 1/20 0.46
POLB P06746 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
PKM P14618 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29009131 0.98 TSHR (0.65) TSHRALDH1A1ERCC5FEN1P2RX7
SCHEMBL28310911 0.92 TSHR (0.59) TSHRALDH1A1ERCC5FEN1P2RX7
SCHEMBL28218932 0.90 TSHR (0.57) TSHRALDH1A1ERCC5FEN1P2RX7
SCHEMBL5285030 0.87 ALDH1A1 (0.52) TSHRALDH1A1ERCC5FEN1P2RX7
Hydrochloric Acid SCHEMBL27715368 0.84 TSHR (0.50) TSHRALDH1A1ERCC5FEN1P2RX7
SCHEMBL7032023 0.83 TSHR (0.71) TSHRALDH1A1ERCC5FEN1P2RX7
SCHEMBL6143391 0.81 CES2 (0.52) TSHRALDH1A1P2RX7CES2CES1
SCHEMBL2831621 0.81 TSHR (0.68) TSHRALDH1A1ERCC5FEN1P2RX7
SCHEMBL29904615 0.81 TSHR (1.00) TSHRALDH1A1ERCC5FEN1P2RX7
SCHEMBL97298 0.81 TSHR (1.00) TSHRALDH1A1ERCC5FEN1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304541-A1 METHYLENE BLUE HAVING A REDUCED CONTENT OF N-NITROSO-AZURE B IMPURITY AND PROCESS FOR OBTAINING THE SAME Icrom S.R.L. (IT) 2025-10-02 US claimed
CN-116178139-A Production method of 2, 3-dichlorobenzoyl chloride 湖北丽康源化工有限公司 2023-05-30 CN claimed
CN-116037052-A Continuous production equipment of 3.5 dichlorobenzoyl chloride 山东兴元化工有限公司 2023-05-02 CN claimed
CN-115779825-A Hydrolysis processing system for processing dichlorobenzoyl chloride and processing method thereof 江苏万隆化学有限公司 2023-03-14 CN claimed
CN-216778835-U High-efficient agitated vessel of two benzoyl chloride production 山东嘉瑞化工有限公司 2022-06-21 CN claimed
CN-215428934-U Catalytic cracking device is used in production of dichlorobenzoyl chloride 酒泉亚佳化学有限公司 2022-01-07 CN claimed
CN-212396726-U Reation kettle for preparation of dichlorobenzoyl chloride 江苏万隆化学有限公司 2021-01-26 CN claimed
CN-212395909-U Distillation still for preparing dichlorobenzoyl chloride 江苏万隆化学有限公司 2021-01-26 CN claimed
CN-109098006-B Cloth-sandwiched rubber material and preparation method thereof 广州机械科学研究院有限公司 2021-01-26 CN claimed
CN-109678698-A A kind of preparation method of 2,4 dichlorobenzyl chloride 江苏佳麦化工有限公司 2019-04-26 CN claimed
WO-2000035888-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF 3,5-DIAMINO-6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZINE VYAS SHARAD KUMAR (IN) 2000-06-22 WO claimed
EP-0963980-A2 1,2,4-Triazine derivative, its preparation and its use as reference marker for testing purity and stability of \"lamotrigine\ THE WELLCOME FOUNDATION LIMITED (GB) 1999-12-15 EP claimed
CN-1238454-A Compound and use thereof WELLCOME FOUND (GB) 1999-12-15 CN claimed
US-5852047-A Pharmaceutical product comprising a salicylate of an esterifiable ace-inhibitor CAL INTERNATIONAL LIMITED (IE) 1998-12-22 US claimed
EP-0741699-A1 A PHARMACEUTICAL PRODUCT COMPRISING A SALICYLATE OF AN ESTERIFIABLE ACE-INHIBITOR CAL INTERNATIONAL LIMITED (IE) 1996-11-13 EP claimed
WO-1995020571-A1 A PHARMACEUTICAL PRODUCT COMPRISING A SALICYLATE OF AN ESTERIFIABLE ACE-INHIBITOR CAL INTERNATIONAL LIMITED (IE) 1995-08-03 WO claimed
US-5334724-A Preparation of substituted 2-chloropyridines BAYER AKTIENGESELLSCHAFT (DE) 1994-08-02 US claimed
EP-0438691-B1 Process for the preparation of substituted 2-chloropyridines BAYER AG (DE) 1994-02-16 EP claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
EP-0438691-A1 Process for the preparation of substituted 2-chloropyridines BAYER AG (DE) 1991-07-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304541-A1 METHYLENE BLUE HAVING A REDUCED CONTENT OF N-NITROSO-AZURE B IMPURITY AND PROCESS FOR OBTAINING THE SAME MMAB, HBB, MB TSHR 3182/4885ALDH1A1 702/4885ERCC5 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.