SCHEMBL28913078

SCHEMBL28913078

ClC(=C(Br)Br)c1cccc(Cl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ERCC5 P28715 1/20 0.42
FEN1 P39748 1/20 0.42
ALDH1A1 P00352 4/20 0.41
P2RX7 Q99572 3/20 0.41
JAK2 O60674 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
PNMT P11086 1/20 0.35
PKM P14618 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28565913 0.82 CES2 (0.50) TSHRERCC5FEN1ALDH1A1CES2
SCHEMBL284889 0.82 TSHR (0.56) TSHRERCC5FEN1ALDH1A1P2RX7
SCHEMBL10438862 0.77 TSHR (0.50) TSHRERCC5FEN1ALDH1A1P2RX7
SCHEMBL2130360 0.77 TSHR (0.60) TSHRERCC5FEN1ALDH1A1P2RX7
SCHEMBL11729147 0.75 TSHR (0.53) TSHRERCC5FEN1ALDH1A1P2RX7
SCHEMBL27379658 0.73 TSHR (0.56) TSHRERCC5FEN1ALDH1A1P2RX7
SCHEMBL21630687 0.73 TSHR (0.56) TSHRERCC5FEN1ALDH1A1P2RX7
SCHEMBL93365 0.73 TSHR (0.68) TSHRERCC5FEN1ALDH1A1P2RX7
Hydrochloric Acid SCHEMBL29009131 0.71 TSHR (0.65) TSHRERCC5FEN1ALDH1A1P2RX7
SCHEMBL6429349 0.70 TSHR (0.43) TSHRERCC5FEN1ALDH1A1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459449-B Styrene-based biaxially stretched sheet, biaxially stretched sheet with antifogging agent layer, packaging container, and heat cooking method 电化株式会社 2021-04-27 CN disclosed