Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.52 |
| ▸ | SUV39H2 | Q9H5I1 | 7/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651242 | 0.94 | SUV39H2 (0.57) | ARSUV39H2CTSKDRD2JAK3 | |
| SCHEMBL5220499 | 0.87 | KDM4D (0.53) | ARSUV39H2CTSKKCNA3RET | |
| SCHEMBL27655935 | 0.87 | SUV39H2 (0.54) | SUV39H2DRD2CNR1CNR2DRD3 | |
| SCHEMBL24508096 | 0.85 | AR (0.51) | ARSUV39H2CTSKKCNA3RET | |
| SCHEMBL29663762 | 0.85 | AR (0.51) | ARSUV39H2CTSKKCNA3RET | |
| SCHEMBL22557377 | 0.83 | AR (0.60) | AR | |
| SCHEMBL5202966 | 0.82 | CTSK (0.53) | SUV39H2CTSKKCNA3RETDRD2 | |
| SCHEMBL25453973 | 0.82 | SUV39H2 (0.50) | SUV39H2DRD2CNR1CNR2DRD3 | |
| SCHEMBL12835697 | 0.82 | SUV39H2 (0.54) | SUV39H2CTSKKCNA3RETJAK3 | |
| SCHEMBL21397261 | 0.81 | SUV39H2 (0.51) | SUV39H2DRD2CNR1CNR2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825657-A | Dual-function chimeric heterocyclic compound for targeted degradation of androgen receptor and application thereof | 成都海创药业有限公司 | 2020-10-27 | — | — | CN | disclosed |