SCHEMBL28489338

SCHEMBL28489338

OCCC(Cl)(Cl)OCC(O)CO

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
USP2 O75604 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27497292 0.82 LMNA (0.36) LMNATHRBALDH1A1KDM4EDUSP3
SCHEMBL15579377 0.81 THRB (0.32) LMNATHRBALDH1A1
SCHEMBL2155545 0.77 LMNA (0.40) LMNATHRBALDH1A1KDM4EDUSP3
SCHEMBL8931433 0.70 LMNA (0.34) LMNAALDH1A1KDM4EDUSP3MEN1
SCHEMBL27561102 0.69 LMNA (0.42) LMNATHRBALDH1A1KDM4EDUSP3
SCHEMBL8083397 0.67 MAPK1 (0.56) LMNATHRBALDH1A1KDM4EDUSP3
SCHEMBL12083370 0.67 MAPK1 (0.56) LMNATHRBALDH1A1KDM4EDUSP3
SCHEMBL27902633 0.67 LMNA (0.40) LMNATHRBALDH1A1KDM4EDUSP3
SCHEMBL6269634 0.67 LMNA (0.40) LMNATHRBALDH1A1KDM4EDUSP3
SCHEMBL116799 0.67 MAPK1 (0.56) LMNATHRBALDH1A1KDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116457023-A antibody-TLR agonist conjugates, methods and uses thereof AMBRX公司 2023-07-18 CN disclosed
CN-111902444-B Etheramine mixtures containing polyetherdiamines and methods of making and using the same 亨斯迈石油化学有限责任公司 2023-07-04 CN disclosed
CN-114163628-A Etheramines and their use as curing agents or intermediates for polymer synthesis 亨斯迈石油化学有限责任公司 2022-03-11 CN disclosed
CN-113999370-A Multifunctional polyamides for protective coatings 亨斯迈先进材料美国有限责任公司 2022-02-01 CN disclosed
CN-109715728-B Adducts and uses thereof 亨斯迈先进材料美国有限责任公司 2021-11-30 CN disclosed
CN-111836851-A Low density epoxy composite structural adhesives for automotive applications 亨斯迈先进材料美国有限责任公司 2020-10-27 CN disclosed