Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514490 | 0.91 | ALDH1A1 (0.35) | ALDH1A1TP53TSHR | |
| SCHEMBL2516026 | 0.78 | PRKCA (0.31) | — | |
| SCHEMBL6753286 | 0.77 | LMNA (0.36) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL11005864 | 0.77 | LMNA (0.36) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2155545 | 0.77 | LMNA (0.40) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL29285409 | 0.76 | LMNA (0.35) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL21043768 | 0.74 | LMNA (0.34) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2515971 | 0.74 | ALDH1A1 (0.32) | ALDH1A1TP53TSHR | |
| SCHEMBL24082887 | 0.74 | — | — | |
| SCHEMBL27497292 | 0.73 | LMNA (0.36) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5600088-A | POLYMERIC COATING OF PRIMARY OR SECONDARY AMINE AND 3-NITRAZAPENTANE DIISOCYANATE FOR PROPELLANT PARTICLES, TO IMPROVE BONDING STRENGTH WITH BINDERS | AEROJET GENERAL CORPORATION (US) | 1997-02-04 | — | — | US | disclosed |