Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21510225 | 0.77 | SLC6A12 (0.43) | GABRR1SLC6A12SLC6A11SLC6A13EPHX1 | |
| SCHEMBL301401 | 0.77 | SLC6A12 (0.43) | GABRR1SLC6A12SLC6A11SLC6A13EPHX1 | |
| SCHEMBL27569047 | 0.77 | SLC6A12 (0.48) | GABRR1GABRR2SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL6427735 | 0.76 | SLC6A12 (0.43) | GABRR1GABRR2SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL28633890 | 0.76 | CA1 (0.43) | EPHX1HSD11B1USP2 | |
| SCHEMBL1927992 | 0.74 | HSD11B1 (0.44) | GABRR1SLC6A12SLC6A11SLC6A13HSD11B1 | |
| SCHEMBL23075049 | 0.73 | — | — | |
| SCHEMBL21400989 | 0.73 | — | — | |
| SCHEMBL22333678 | 0.73 | — | — | |
| SCHEMBL20865149 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262367-A2 | ORAL PHARMACEUTICAL COMPOSITIONS OF BUPRENORPHINE AND METHOD OF USE | Theraquest Biosciences, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009114118-A2 | ORAL PHARMACEUTICAL COMPOSITIONS OF BUPRENORPHINE AND METHOD OF USE | THERAQUEST BIOSCIENCES, INC. (US) | 2009-09-17 | — | — | WO | disclosed |