Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | CASP6 | P55212 | 1/20 | 0.69 |
| ▸ | CDC42 | P60953 | 1/20 | 0.66 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.53 |
| ▸ | BRD3 | Q15059 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28489487 | 0.83 | PRMT5 (0.59) | GAACASP6CDC42PRMT5BRD3 | |
| SCHEMBL13925739 | 0.82 | GAA (0.73) | GAACASP6CDC42PRMT5BRD3 | |
| Hydrochloric Acid SCHEMBL4154675 | 0.81 | GAA (0.75) | GAACASP6CDC42PRMT5BRD3 | |
| SCHEMBL20180909 | 0.80 | CDC42 (1.00) | GAACASP6CDC42PRMT5BRD3 | |
| SCHEMBL5454054 | 0.80 | CDC42 (1.00) | GAACASP6CDC42PRMT5BRD3 | |
| SCHEMBL22118719 | 0.78 | CYP2D6 (0.55) | GAACASP6CDC42PRMT5BRD3 | |
| SCHEMBL28731952 | 0.78 | CYP2D6 (0.55) | GAACASP6CDC42PRMT5BRD3 | |
| SCHEMBL31497455 | 0.77 | RB1 (0.52) | GAACASP6CDC42PRMT5BRD3 | |
| SCHEMBL20615429 | 0.77 | AR (0.49) | MAPTALOX15SMN1; SMN2MAPK1AR | |
| SCHEMBL21996536 | 0.76 | GAA (0.67) | GAACASP6CDC42PRMT5BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739371-B | Tetrahydrocarbazole micromolecule organic compound, application thereof in preparing antibacterial drugs and preparation method thereof | 华东师范大学 | 2020-08-25 | — | — | CN | disclosed |