Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336316 | 0.78 | AR (0.46) | ARPGR | |
| SCHEMBL28432119 | 0.73 | AR (0.36) | ARPGRTRPV4MAOAMAOB | |
| SCHEMBL2375554 | 0.73 | TRPV4 (0.39) | ARPGRTRPV4MAOAMAOB | |
| SCHEMBL1395550 | 0.72 | CA2 (0.41) | ARPGRMAOAMAOB | |
| SCHEMBL26259669 | 0.69 | ALDH1A1 (0.34) | ARPGR | |
| SCHEMBL28608570 | 0.68 | AR (0.39) | AR | |
| SCHEMBL31399295 | 0.68 | TSHR (0.39) | ARPGRTRPV4MAOAMAOB | |
| SCHEMBL152358 | 0.68 | TSHR (0.39) | ARPGRTRPV4MAOAMAOB | |
| SCHEMBL23542393 | 0.68 | CA2 (0.46) | AR | |
| SCHEMBL23084783 | 0.68 | AR (0.43) | ARTRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175310-B | Asymmetric aza diisoindole methylene compound and its synthesis and use of boron fluoride compound | 南京大学 | 2020-11-13 | — | — | CN | disclosed |