SCHEMBL28489986

SCHEMBL28489986

COc1ccc(CON(N)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
LTA4H P09960 1/20 0.50
AOC3 Q16853 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAOB P27338 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
ABCB1 P08183 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SIGMAR1 Q99720 1/20 0.42
CA4 P22748 1/20 0.42
FABP7 O15540 1/20 0.42
FABP5 Q01469 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4944239 0.84 IDO1 (0.48) IDO1AGXTAOC3L3MBTL1MAOB
Hydrochloric Acid SCHEMBL9080783 0.82 AGXT (0.50) IDO1AGXTAOC3L3MBTL1MAOB
SCHEMBL21443899 0.79 LTA4H (0.53) IDO1AGXTLTA4HAOC3L3MBTL1
SCHEMBL3590270 0.76 LTA4H (0.46) IDO1AGXTLTA4HL3MBTL1TDP1
SCHEMBL11052720 0.76 LTA4H (0.53) LTA4HAOC3TDP1MEN1KMT2A
SCHEMBL12960568 0.75 LTA4H (0.52) IDO1AGXTLTA4HL3MBTL1TDP1
SCHEMBL20917237 0.75 LTA4H (0.56) IDO1AGXTLTA4HL3MBTL1TDP1
SCHEMBL29071354 0.74 NPC1 (0.51) TDP1NPC1RAB9AMEN1KMT2A
SCHEMBL7626558 0.72 CA4 (0.54) LTA4HTDP1KMT2ACA4
SCHEMBL3036840 0.72 LTA4H (0.69) IDO1AGXTLTA4HL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114531850-A Pharmaceutical composition and kit characterized by containing novel penicillin derivative or salt thereof and 1 or more compounds selected from beta-lactamase inhibitory compound and antibacterial compound or salt thereof 富士胶片株式会社 2022-05-24 CN disclosed
CN-111954673-A Novel penam derivative or salt thereof, pharmaceutical composition, and use thereof 富士胶片株式会社 2020-11-17 CN disclosed