SCHEMBL28490307

SCHEMBL28490307

CCCc1ccc(C)cc1CCC.N[SH](=O)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PRKCI P41743 1/20 0.33
MAPT P10636 3/20 0.32
HTT P42858 2/20 0.32
SRC P12931 1/20 0.32
AMY1A P0DUB6 1/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
APOBEC3A P31941 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10822849 0.86 TAAR1 (0.43) TAAR1HSD17B10TSHRLDHALDHB
SCHEMBL9629541 0.84 TAAR1 (0.42) TAAR1HSD17B10TSHRLDHALDHB
SCHEMBL28480935 0.84 TAAR1 (0.42) TAAR1HSD17B10MAPTHTTSRC
Hydrogen Peroxide SCHEMBL11334349 0.82 LDHA (0.42) TAAR1HSD17B10TSHRLDHALDHB
SCHEMBL27393197 0.81 PRKCI (0.38) TSHRMEN1KMT2APRKCIMAPT
SCHEMBL14614986 0.80 TAAR1 (0.48) TAAR1HSD17B10TSHRAMY1ANOS3
SCHEMBL28416322 0.80 TYR (0.46) TAAR1HSD17B10TSHRMEN1KMT2A
SCHEMBL28344465 0.77 ADRA2A (0.38) TAAR1TP53
SCHEMBL14110339 0.77 NPSR1 (0.52) TSHRMEN1KMT2AMAPTSRC
SCHEMBL28135229 0.77 ICMT (0.41) TAAR1LDHALDHBPRKCIHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107954906-B Synthetic method of aryl sulfonyl tertiary amine compound 西北师范大学 2020-10-16 CN disclosed