Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807369 | 0.86 | AGTR2 (0.49) | — | |
| SCHEMBL27827984 | 0.86 | AGTR2 (0.49) | — | |
| SCHEMBL17103461 | 0.78 | PKM (0.55) | POLBPKMNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL27377437 | 0.78 | PKM (0.55) | POLBPKMNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL17103459 | 0.78 | PKM (0.55) | POLBPKMNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL2977297 | 0.76 | MEN1 (0.55) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL18410317 | 0.76 | HTR2C (0.56) | POLBPKMNPSR1L3MBTL1MEN1 | |
| SCHEMBL20296331 | 0.76 | HTR2C (0.56) | POLBPKMNPSR1L3MBTL1MEN1 | |
| SCHEMBL8350324 | 0.75 | PKM (0.49) | POLBPKMNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL2605500 | 0.75 | PKM (0.49) | POLBPKMNPSR1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498762-B | Synthesis method of (2S,5R) -5- [ (benzyloxy) amino ] -piperidine-2-ethyl formate | 山东安信制药有限公司 | 2020-10-27 | — | — | CN | disclosed |