Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661392 | 0.74 | PCSK9 (0.43) | EGLN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL5327965 | 0.71 | — | — | |
| SCHEMBL27936100 | 0.66 | ALDH1A1 (0.40) | EGLN2NPC1RAB9AALDH1A1HTR6 | |
| SCHEMBL16048402 | 0.66 | SLC6A2 (0.35) | — | |
| SCHEMBL3709944 | 0.66 | HTR2A (0.50) | — | |
| SCHEMBL426228 | 0.62 | NOS1 (0.32) | — | |
| SCHEMBL12277785 | 0.62 | TDP1 (0.48) | TDP1KDM4EAPOBEC3GHSD11B1NPSR1 | |
| SCHEMBL5804004 | 0.62 | — | — | |
| SCHEMBL2274673 | 0.62 | EGLN2 (0.44) | EGLN2KDM4ENPC1RAB9ANOTUM | |
| SCHEMBL197834 | 0.62 | ACHE (0.47) | KDM4ENPC1RAB9ANPSR1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527067-B | Process for the preparation of 1- [5- (2-fluorophenyl) -1- (pyridin-3-ylsulfonyl) -1H-pyrrol-3-yl ] -N-methylmethylamine monofumarate | 日本化学药品株式会社 | 2024-06-25 | — | — | CN | disclosed |
| CN-111527067-A | Process for producing 1- [ 5- (2-fluorophenyl) -1- (pyridin-3-ylsulfonyl) -1H-pyrrol-3-yl ] -N-methylmethanemethanemetic acid salt | 日本化学药品株式会社 | 2020-08-11 | — | — | CN | disclosed |