Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283533 | 0.91 | TSHR (0.81) | TSHRCNR2CRHBPCRHR2NR1H2 | |
| SCHEMBL3385658 | 0.87 | ALDH1A1 (0.59) | TSHRCNR2S1PR1SIGMAR1ALDH1A1 | |
| SCHEMBL179996 | 0.85 | TSHR (1.00) | TSHRCNR2NR1H2NR1H3ALDH1A1 | |
| SCHEMBL12774515 | 0.84 | TSHR (0.70) | TSHRCNR2CRHBPCRHR2NR1H2 | |
| SCHEMBL1224833 | 0.84 | TSHR (0.70) | TSHRCNR2CRHBPCRHR2NR1H2 | |
| SCHEMBL13061113 | 0.83 | TSHR (0.50) | TSHRCRHBPCRHR2NR1H2NR1H3 | |
| SCHEMBL20119625 | 0.83 | TSHR (0.81) | TSHRCNR2NR1H2NR1H3ALDH1A1 | |
| SCHEMBL11440294 | 0.83 | ALDH1A1 (0.71) | TSHRCNR2CRHBPCRHR2NR1H2 | |
| SCHEMBL11136965 | 0.83 | TSHR (0.68) | TSHRCNR2CRHBPCRHR2NR1H2 | |
| SCHEMBL11682124 | 0.83 | TSHR (0.68) | TSHRCNR2CRHBPCRHR2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995879-B | Method for enhancing alkali resistance and oxidation resistance of benzisothiazole disperse dye | 青岛大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-111995879-A | Method for enhancing alkali resistance and oxidation resistance of benzisothiazole disperse dye | 青岛大学 | 2020-11-27 | — | — | CN | disclosed |