Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194795 | 0.87 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRCNR2TERT | |
| SCHEMBL28490683 | 0.87 | TSHR (0.72) | ALDH1A1CYP3A4TSHRSIGMAR1CNR2 | |
| SCHEMBL9446165 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRSIGMAR1THRB | |
| SCHEMBL20171826 | 0.85 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRSIGMAR1S1PR1 | |
| SCHEMBL9829524 | 0.84 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRSIGMAR1CNR2 | |
| SCHEMBL1574035 | 0.84 | ALDH1A1 (0.71) | ALDH1A1CYP3A4TSHRCNR2TERT | |
| SCHEMBL7672423 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRCNR2TERT | |
| SCHEMBL13778840 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRCNR2TERT | |
| SCHEMBL3510031 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRCNR2TERT | |
| SCHEMBL8126760 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRCNR2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363353-A1 | Method for Improving Alkali Resistance and Oxidation Resistance of Benzisothiazole Disperse Dye | Penglai Jiaxin Dye Chemical Co., LTD (CN) | 2021-11-25 | — | — | US | disclosed |
| CN-111995879-B | Method for enhancing alkali resistance and oxidation resistance of benzisothiazole disperse dye | 青岛大学 | 2021-10-08 | — | — | CN | disclosed |
| US-11116772-B2 | Medical methods utilising high purity diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2021-09-14 | — | — | US | disclosed |
| CN-111995879-A | Method for enhancing alkali resistance and oxidation resistance of benzisothiazole disperse dye | 青岛大学 | 2020-11-27 | — | — | CN | disclosed |
| US-20200268767-A1 | MEDICAL METHODS UTILISING HIGH PURITY DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LIMITED (SG) | 2020-08-27 | — | — | US | disclosed |
| US-20180078562-A1 | MEDICAL METHODS UTILISING HIGH PURITY DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2018-03-22 | — | — | US | disclosed |
| EP-2004155-B1 | INHIBITORS OF PROTEIN AGGREGATION | WISTA LAB LTD (SG) | 2018-02-21 | — | — | EP | disclosed |
| EP-2004155-B1 | INHIBITORS OF PROTEIN AGGREGATION | WISTA LAB LTD (SG) | 2018-02-21 | — | — | EP | disclosed |
| EP-2853293-B1 | Thioninium compounds and their use | WISTA LAB LTD (SG) | 2017-11-22 | — | — | EP | disclosed |
| EP-2853293-B1 | Thioninium compounds and their use | WISTA LAB LTD (SG) | 2017-11-22 | — | — | EP | disclosed |
| EP-0148009-A2 | Process for the alkylation of aromatic amines and use of the products thereof | ETHYL CORPORATION (US) | 1985-07-10 | — | — | EP | disclosed |
| US-4494989-A | PRESSURE SENSITIVE CARBONLESS DUPLICATING OR THERMAL MARKING SYSTEMS | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-01-22 | — | — | US | disclosed |
| US-4459186-A | Electrochemical oxidation of alkyl aromatic compounds | UOP INC. (US) | 1984-07-10 | — | — | US | disclosed |
| EP-0073277-A1 | Process for producing orthoalkylated aromatic amines | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1983-03-09 | — | — | EP | disclosed |
| US-4351958-A | Process for producing orthoalkylated aromatic amine | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-09-28 | — | — | US | disclosed |
| US-4257954-A | INDOLYL-PHENYLSULFONYL-PHENYL METHANE | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4251629-A | COLORIMETRY, USING 4-AMINOANTIPYRENE, N-SUBSTITUTED ANILINE, ACTIVATOR | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4180503-A | FOR DYEING POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-25 | — | — | US | disclosed |
| US-4124581-A | FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-07 | — | — | US | disclosed |
| US-4020068-A | Chromogenic furoquinoxalines | NCR CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11116772-B2 | Medical methods utilising high purity diaminophenothiazinium compounds | MGMT, MAPT, TST | ALDH1A1 3409/4885CYP3A4 3944/4885TSHR 1274/4885 |
| US-20180078562-A1 | MEDICAL METHODS UTILISING HIGH PURITY DIAMINOPHENOTHIAZINIUM COMPOUNDS | MGMT, MAPT, TST | ALDH1A1 3735/4885CYP3A4 3739/4885TSHR 1506/4885 |
| US-20200268767-A1 | MEDICAL METHODS UTILISING HIGH PURITY DIAMINOPHENOTHIAZINIUM COMPOUNDS | MGMT, MAPT, TST | ALDH1A1 3735/4885CYP3A4 3739/4885TSHR 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.