Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL28658378 | 0.87 | MAPT (0.38) | TSHRALDH1A1GAAMAPTLMNA | |
| Oxalic Acid SCHEMBL8507926 | 0.82 | MAPT (0.39) | TSHRALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL34259 | 0.81 | GAA (0.48) | GAAMAPT | |
| Maleic Acid SCHEMBL4504225 | 0.81 | ALDH1A1 (0.37) | ALDH1A1GAAMAPTLMNANPC1 | |
| Fumaric Acid SCHEMBL4504232 | 0.81 | ALDH1A1 (0.37) | ALDH1A1GAAMAPTLMNANPC1 | |
| Water SCHEMBL4672877 | 0.79 | GAA (0.46) | GAAMAPTNPC1RAB9AHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL4151802 | 0.79 | GAA (0.46) | GAAMAPT | |
| SCHEMBL1787947 | 0.79 | GAA (0.46) | GAAMAPT | |
| Bromide SCHEMBL10654286 | 0.79 | GAA (0.46) | GAAMAPT | |
| Iodide SCHEMBL12466756 | 0.79 | GAA (0.46) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943911-B | Acrylamidobenzazepine derivatives as GSK-3 beta inhibitors and uses thereof | 复旦大学 | 2022-12-30 | — | — | CN | claimed |
| CN-111943911-B | Acrylamidobenzazepine derivatives as GSK-3 beta inhibitors and uses thereof | 复旦大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-111943911-B | Acrylamidobenzazepine derivatives as GSK-3 beta inhibitors and uses thereof | 复旦大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-111943911-A | Acrylamidobenzazepine derivatives as GSK-3 beta inhibitors and their use | 复旦大学 | 2020-11-17 | — | — | CN | disclosed |
| CN-111943911-A | Acrylamidobenzazepine derivatives as GSK-3 beta inhibitors and their use | 复旦大学 | 2020-11-17 | — | — | CN | disclosed |