Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770460 | 0.76 | ATR (0.38) | KDM4EATRMAPTBRD9MEN1 | |
| SCHEMBL2970156 | 0.75 | GPR35 (0.48) | LCKKDM4EALDH1A1ATRGAA | |
| SCHEMBL7412635 | 0.75 | LCK (0.43) | LCKATRCA12CA1CA9 | |
| SCHEMBL21871197 | 0.74 | CA12 (0.46) | LCKSORT1CA12CA1CA9 | |
| SCHEMBL31329817 | 0.74 | LCK (0.40) | LCKATRBRD9MEN1KMT2A | |
| SCHEMBL8201135 | 0.72 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10POLBMAPT | |
| SCHEMBL12233051 | 0.72 | MAPKAPK2 (0.44) | LCKATRMEN1NPC1GAA | |
| SCHEMBL30493907 | 0.72 | KEAP1 (0.51) | LCKPOLBATRMEN1NPC1 | |
| SCHEMBL21238856 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL27537751 | 0.72 | LCK (0.44) | LCKKDM4EATRMAPTBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902404-A | Therapeutic compounds and compositions | 艾克赛特赫拉制药有限责任公司 | 2020-11-06 | — | — | CN | disclosed |