SCHEMBL28494263

SCHEMBL28494263

CC=CC(=O)CCC[Si](O)(O)O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
POLB P06746 1/20 0.32
POLA1 P09884 1/20 0.32
PPARG P37231 2/20 0.31
PPARA Q07869 2/20 0.31
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5981266 0.85 TRPA1 (0.34) TRPA1POLBPOLA1PPARGPPARA
SCHEMBL565538 0.83 TRPA1 (0.35) TRPA1POLBPOLA1PPARGPPARA
SCHEMBL724849 0.78 POLB (0.36) TRPA1POLBPOLA1
SCHEMBL21894041 0.77 SOAT1 (0.38) TRPA1POLBPOLA1PPARGPPARA
SCHEMBL1305971 0.76 POLB (0.35) TRPA1POLBPOLA1
SCHEMBL615170 0.75 TRPA1 (0.34) TRPA1POLBPOLA1PPARGPPARA
SCHEMBL960509 0.75 POLB (0.34) TRPA1POLBPOLA1
SCHEMBL160883 0.75
SCHEMBL4201474 0.75
SCHEMBL178873 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142926-A Curable composition, laminate, and automobile headlamp lens 三菱化学株式会社 2020-12-29 CN disclosed