Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175274 | 0.83 | — | — | |
| SCHEMBL724849 | 0.81 | POLB (0.36) | POLBPOLA1TRPA1 | |
| SCHEMBL3799645 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL565538 | 0.79 | TRPA1 (0.35) | POLBPOLA1TRPA1 | |
| SCHEMBL615170 | 0.79 | TRPA1 (0.34) | POLBPOLA1TRPA1 | |
| SCHEMBL35808 | 0.77 | ATM (0.44) | — | |
| SCHEMBL8644260 | 0.77 | ATM (0.44) | — | |
| SCHEMBL5981266 | 0.77 | TRPA1 (0.34) | POLBPOLA1TRPA1 | |
| SCHEMBL10025716 | 0.77 | ATM (0.38) | POLBPOLA1 | |
| SCHEMBL1305971 | 0.76 | POLB (0.35) | POLBPOLA1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877829-B2 | Process for making cationic hydrophilic siloxanyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2014-11-04 | — | — | US | claimed |
| EP-2287169-A1 | Process for making cationic hydrophilic siloxanyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2011-02-23 | — | — | EP | claimed |
| US-20110015298-A1 | PROCESS FOR MAKING CATIONIC HYDROPHILIC SILOXANYL MONOMERS | SANTARUS, INC. | 2011-01-20 | — | — | US | claimed |
| US-7825273-B2 | dissolving hydride containing siloxane compound in solvent, treating with allylic halide and hydrosilation catalyst, heating under nitrogen atmosphere for quantitative loss of reactants, cooling, concentrating, treating with tertiary amino-vinyl compound, heating; for biocompatible ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2010-11-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015298-A1 | PROCESS FOR MAKING CATIONIC HYDROPHILIC SILOXANYL MONOMERS | ILK, SAMM50, AAAS | POLB 1496/4885POLA1 1877/4885TRPA1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.