Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17456836 | 0.83 | GPR3 (0.44) | POLBGPR3KMT2AGAAHDAC3 | |
| SCHEMBL8999545 | 0.72 | GPR3 (0.54) | POLBGPR3KMT2AHDAC3HDAC4 | |
| SCHEMBL3044362 | 0.72 | GPR3 (0.46) | POLBGPR3KMT2AGAAHDAC3 | |
| SCHEMBL6502792 | 0.72 | KMT2A (0.47) | POLBGPR3KMT2AGAAHDAC3 | |
| SCHEMBL4603276 | 0.71 | GPR3 (0.41) | POLBGPR3KMT2AGAAHDAC3 | |
| SCHEMBL4600049 | 0.71 | GPR3 (0.41) | POLBGPR3KMT2AGAAHDAC3 | |
| SCHEMBL30510362 | 0.71 | GPR3 (0.41) | POLBGPR3KMT2AGAAHDAC3 | |
| SCHEMBL1830100 | 0.71 | GPR3 (0.41) | POLBGPR3KMT2AGAAHDAC3 | |
| SCHEMBL31355068 | 0.71 | GPR3 (0.41) | POLBGPR3KMT2AGAAHDAC3 | |
| SCHEMBL30510269 | 0.71 | GPR3 (0.41) | POLBGPR3KMT2AGAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062693-A | Synthetic method of 2- (9H-fluorene-9-methoxycarbonylamino) -3-methyl-2-butenoic acid | 上海吉奉生物科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-112062693-A | Synthetic method of 2- (9H-fluorene-9-methoxycarbonylamino) -3-methyl-2-butenoic acid | 上海吉奉生物科技有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-112062693-A | Synthetic method of 2- (9H-fluorene-9-methoxycarbonylamino) -3-methyl-2-butenoic acid | 上海吉奉生物科技有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-112062693-A | Synthetic method of 2- (9H-fluorene-9-methoxycarbonylamino) -3-methyl-2-butenoic acid | 上海吉奉生物科技有限公司 | 2020-12-11 | — | — | CN | disclosed |