SCHEMBL284952

SCHEMBL284952

N#CC1=C2CC=CC=C2N(CCCCCC(=O)O)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.39
▸ DUSP3 P51452 1/20 0.39
▸ MCL1 Q07820 1/20 0.39
▸ CTDSP1 Q9GZU7 1/20 0.39
▸ KAT2B Q92831 4/20 0.37
▸ EP300 Q09472 3/20 0.37
▸ CREBBP Q92793 3/20 0.37
▸ KAT2A Q92830 3/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ CDC25A P30304 9/20 0.35
▸ PKM P14618 1/20 0.35
▸ PTGIR P43119 2/20 0.35
▸ HDAC3 O15379 1/20 0.35
▸ TUBB4A P04350 1/20 0.35
▸ TUBB P07437 1/20 0.35
▸ TUBA3C P0DPH7 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ TUBA1B P68363 1/20 0.35
▸ TUBA4A P68366 1/20 0.35
▸ TUBB4B P68371 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3775706 0.82 MAPT (0.40) MAPTDUSP3MCL1CTDSP1KAT2B
SCHEMBL284852 0.73 SMN1; SMN2 (0.39) MAPTDUSP3MCL1CTDSP1KAT2B
SCHEMBL285364 0.67 LMNA (0.40) SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
SCHEMBL284853 0.64 HDAC3 (0.56) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL9350109 0.64 HDAC8 (0.69) SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
SCHEMBL4202491 0.64 HDAC8 (0.69) SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
SCHEMBL133529 0.64 HDAC8 (0.69) SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
SCHEMBL3468927 0.64 HDAC8 (0.69) SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
SCHEMBL9899475 0.64 HDAC8 (0.69) SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
SCHEMBL9130049 0.64 HDAC8 (0.69) SMN1; SMN2HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9580749-B2 Dyes and labeled molecules BIOTIUM, INC. (US) 2017-02-28 — — US disclosed
US-9102835-B2 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. (US) 2015-08-11 — — US disclosed
US-8753814-B2 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. (US) 2014-06-17 — — US disclosed
US-20140106349-A1 Dyes and Labeled Molecules ALLELOGIC BIOSCIENCES CORPORATION (US) 2014-04-17 — — US disclosed
US-20140073058-A1 Methods of Using Dyes in Association with Nucleic Acid Staining or Detection and Associated Technology BIOTIUM, INC. (US) 2014-03-13 — — US disclosed
US-8530195-B2 Dyes and labeled molecules BIOTIUM, INC. (US) 2013-09-10 — — US disclosed
US-20130167309-A1 METHODS OF USING DYES IN ASSOCIATION WITH NUCLEIC ACID STAINING OR DETECTION AND ASSOCIATED TECHNOLOGY BIOTIUM, INC. (US) 2013-07-04 — — US disclosed
EP-2428586-B1 Dimeric nucleic acid dyes, and associated systems and methods BIOTIUM INC (US) 2013-05-08 — — EP disclosed
US-8232050-B2 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. (US) 2012-07-31 — — US disclosed
EP-2428586-A1 Dimeric and trimeric nucleic acid dyes, and associated systems and methods Biotium Inc. (US) 2012-03-14 — — EP disclosed
US-20100317016-A1 DYES AND LABELED MOLECULES BIOTIUM, INC. (US) 2010-12-16 — — US disclosed
US-7803943-B2 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. (US) 2010-09-28 — — US disclosed
US-7776567-B2 Dimeric and trimeric nucleic acid dyes, and associated systems and methods BIOTIUM, INC. (US) 2010-08-17 — — US disclosed
US-20100009454-A1 METHODS OF USING DYES IN ASSOCIATION WITH NUCLEIC ACID STAINING OR DETECTION AND ASSOCIATED TECHNOLOGY BIOTIUM, INC. 2010-01-14 — — US disclosed
US-7601498-B2 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. (US) 2009-10-13 — — US disclosed
EP-1863933-A4 DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS BIOTIUM INC (US) 2009-04-08 — — EP disclosed
EP-1863933-A2 DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS Biotium Inc. (US) 2007-12-12 — — EP disclosed
US-20060211029-A1 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. 2006-09-21 — — US disclosed
WO-2006099605-A2 DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS BIOTIUM, INC. (US) 2006-09-21 — — WO disclosed
US-20060211028-A1 Dimeric and trimeric nucleic acid dyes, and associated systems and methods ALLELOGIC BIOSCIENCES CORPORATION 2006-09-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317016-A1 DYES AND LABELED MOLECULES DNA2, POLL, POLRMT MAPT 2935/4885DUSP3 4562/4885MCL1 1232/4885
US-20060211028-A1 Dimeric and trimeric nucleic acid dyes, and associated systems and methods DNA2, POLRMT, POLL MAPT 2333/4885DUSP3 3620/4885MCL1 1912/4885
US-20060211029-A1 Methods of using dyes in association with nucleic acid staining or detection and associated technology HNRNPLL, HNRNPL, HNRNPH3 MAPT 2955/4885DUSP3 4436/4885MCL1 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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