Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284852 | 0.91 | SMN1; SMN2 (0.39) | TSHRALDH1A1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL285425 | 0.88 | DRD2 (0.45) | HDAC8HDAC6HDAC1CYP3A4DRD2 | |
| SCHEMBL284874 | 0.85 | DRD2 (0.42) | ALDH1A1HDAC8HDAC6HDAC1CYP1A2 | |
| SCHEMBL1110825 | 0.81 | DRD2 (0.34) | LMNAALDH1A1SMN1; SMN2HDAC8KDM4E | |
| Bromide SCHEMBL284958 | 0.78 | NAMPT (0.39) | LMNAALDH1A1HDAC8CYP1A2CYP3A4 | |
| SCHEMBL591245 | 0.77 | CDC25A (0.40) | LMNAALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL284859 | 0.76 | TDP1 (0.43) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL285430 | 0.76 | CHRM2 (0.31) | CYP3A4HTR1ADRD2 | |
| SCHEMBL19656192 | 0.74 | CYP1A2 (0.35) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL285365 | 0.74 | HDAC8 (0.57) | LMNATSHRALDH1A1SMN1; SMN2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580749-B2 | Dyes and labeled molecules | BIOTIUM, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-9102835-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-8753814-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20140106349-A1 | Dyes and Labeled Molecules | ALLELOGIC BIOSCIENCES CORPORATION (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140073058-A1 | Methods of Using Dyes in Association with Nucleic Acid Staining or Detection and Associated Technology | BIOTIUM, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-8530195-B2 | Dyes and labeled molecules | BIOTIUM, INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-20130167309-A1 | METHODS OF USING DYES IN ASSOCIATION WITH NUCLEIC ACID STAINING OR DETECTION AND ASSOCIATED TECHNOLOGY | BIOTIUM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| EP-2428586-B1 | Dimeric nucleic acid dyes, and associated systems and methods | BIOTIUM INC (US) | 2013-05-08 | — | — | EP | disclosed |
| US-8232050-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2012-07-31 | — | — | US | disclosed |
| EP-2428586-A1 | Dimeric and trimeric nucleic acid dyes, and associated systems and methods | Biotium Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100317016-A1 | DYES AND LABELED MOLECULES | BIOTIUM, INC. (US) | 2010-12-16 | — | — | US | disclosed |
| US-7803943-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-7776567-B2 | Dimeric and trimeric nucleic acid dyes, and associated systems and methods | BIOTIUM, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20100009454-A1 | METHODS OF USING DYES IN ASSOCIATION WITH NUCLEIC ACID STAINING OR DETECTION AND ASSOCIATED TECHNOLOGY | BIOTIUM, INC. | 2010-01-14 | — | — | US | disclosed |
| US-7601498-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| EP-1863933-A4 | DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS | BIOTIUM INC (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1863933-A2 | DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS | Biotium Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006099605-A2 | DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS | BIOTIUM, INC. (US) | 2006-09-21 | — | — | WO | disclosed |
| US-20060211029-A1 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. | 2006-09-21 | — | — | US | disclosed |
| US-20060211028-A1 | Dimeric and trimeric nucleic acid dyes, and associated systems and methods | ALLELOGIC BIOSCIENCES CORPORATION | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317016-A1 | DYES AND LABELED MOLECULES | DNA2, POLL, POLRMT | LMNA 147/4885TSHR 1524/4885ALDH1A1 2689/4885 |
| US-20060211028-A1 | Dimeric and trimeric nucleic acid dyes, and associated systems and methods | DNA2, POLRMT, POLL | LMNA 207/4885TSHR 1701/4885ALDH1A1 3456/4885 |
| US-20060211029-A1 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | HNRNPLL, HNRNPL, HNRNPH3 | LMNA 156/4885TSHR 2732/4885ALDH1A1 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.