Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19873098 | 0.86 | MAPT (0.44) | ENPP1ENPP3DHFRPPARGPPARA | |
| SCHEMBL29222580 | 0.86 | DHFR (0.46) | ENPP1ENPP3GPR84ACHEDHFR | |
| SCHEMBL29211542 | 0.82 | PIM1 (0.40) | GPR84PPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL4895197 | 0.81 | GPR84 (0.48) | ENPP1GPR84ACHEPPARGMCL1 | |
| SCHEMBL22978418 | 0.81 | ENPP1 (0.46) | ENPP1ENPP3GPR84DHFRPPARG | |
| SCHEMBL16105349 | 0.81 | TNF (0.52) | ENPP1ENPP3PPARGPPARACYP2C9 | |
| SCHEMBL29995332 | 0.81 | TNF (0.52) | ENPP1ENPP3PPARGPPARACYP2C9 | |
| SCHEMBL31598886 | 0.80 | KDM4E (0.41) | ENPP1DHFRPPARGPPARACYP2C9 | |
| SCHEMBL29707931 | 0.79 | CYP1A2 (0.43) | ENPP1GPR84CYP2C9FLT3ALDH1A1 | |
| SCHEMBL4312191 | 0.79 | ALDH1A1 (0.46) | ENPP1DHFRCYP2C9CYP2C19MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135808-A | Materials for forming nucleation inhibiting coatings and devices incorporating same | OTI照明公司 | 2020-12-25 | — | — | CN | disclosed |