Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | KLK7 | P49862 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | BCL2 | P10415 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470732 | 0.87 | ALOX15 (0.69) | RAB9AMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10561558 | 0.86 | RAB9A (0.64) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 | |
| Formonetin SCHEMBL4728656 | 0.84 | RAB9A (0.83) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13169484 | 0.84 | RAB9A (0.74) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29448332 | 0.81 | RAB9A (0.90) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 | |
| Castanin SCHEMBL572274 | 0.79 | RAB9A (1.00) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 | |
| Formononetin SCHEMBL15271536 | 0.76 | KDM4E (1.00) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 | |
| Formononetin SCHEMBL62915 | 0.76 | KDM4E (1.00) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 | |
| Formononetin SCHEMBL29361145 | 0.76 | KDM4E (1.00) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7030328 | 0.76 | RAB9A (0.81) | RAB9AKLK7MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759554-B | Hydroxypropyl isoflavone compound and preparation method and application thereof | 云南中烟工业有限责任公司 | 2020-08-25 | — | — | CN | claimed |
| CN-107759554-B | Hydroxypropyl isoflavone compound and preparation method and application thereof | 云南中烟工业有限责任公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-107759554-B | Hydroxypropyl isoflavone compound and preparation method and application thereof | 云南中烟工业有限责任公司 | 2020-08-25 | — | — | CN | disclosed |