Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28498473 | 0.86 | SMN1; SMN2 (0.42) | MTNR1AMTNR1BTARBP2POLBGAA | |
| SCHEMBL28498344 | 0.83 | NQO2 (0.40) | NQO2TARBP2POLBGAARAB9A | |
| SCHEMBL28494985 | 0.82 | KMT2A (0.43) | TARBP2POLBGAARAB9A | |
| SCHEMBL28493487 | 0.81 | GAA (0.37) | TARBP2POLBGAARAB9A | |
| SCHEMBL28496550 | 0.79 | POLB (0.43) | TARBP2POLBGAARAB9A | |
| SCHEMBL28498336 | 0.77 | NPC1 (0.46) | TARBP2GAARAB9A | |
| SCHEMBL28491356 | 0.77 | ALDH1A1 (0.40) | MTNR1AMTNR1BPOLBRAB9A | |
| SCHEMBL28497451 | 0.77 | MTNR1A (0.40) | MTNR1ANQO2TARBP2POLBGAA | |
| SCHEMBL28494815 | 0.77 | RAB9A (0.47) | RAB9A | |
| SCHEMBL28498699 | 0.74 | POLB (0.46) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110932-B | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112110932-A | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |