Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.45 |
| ▸ | PDE4A | P27815 | 9/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17292789 | 0.71 | DAPK3 (0.54) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL2558595 | 0.68 | ALDH1A1 (0.45) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL12844979 | 0.68 | ALDH1A1 (0.45) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL2078062 | 0.66 | ALDH1A1 (0.43) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL1149887 | 0.66 | PDE5A (0.52) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL3100667 | 0.65 | PDPK1 (0.56) | ALDH1A1HPGDBLMHSD17B10 | |
| SCHEMBL409487 | 0.65 | PIK3CD (0.51) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28494361 | 0.65 | ADORA2B (0.36) | ADORA2BADORA2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL24023138 | 0.65 | HRH3 (0.58) | ADORA2B | |
| SCHEMBL21643912 | 0.65 | HRH3 (0.40) | ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-112135818-A | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-112135818-A | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2020-12-25 | — | — | CN | disclosed |