Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689581 | 0.94 | HTT (0.53) | HTTHPGDALDH1A1POLBTHRB | |
| SCHEMBL29983521 | 0.85 | EPHX1 (0.41) | HTTHPGDALDH1A1POLBTHRB | |
| SCHEMBL17560438 | 0.74 | HTT (0.48) | HTTHPGDALDH1A1POLBTHRB | |
| SCHEMBL29124849 | 0.72 | ALDH1A1 (0.45) | HTTHPGDALDH1A1POLBTHRB | |
| SCHEMBL3399580 | 0.72 | ALDH1A1 (0.45) | HTTHPGDALDH1A1POLBTHRB | |
| SCHEMBL17560382 | 0.72 | ALDH1A1 (0.41) | HTTHPGDALDH1A1POLBHSD11B1 | |
| SCHEMBL17560371 | 0.71 | ALDH1A1 (0.49) | HTTHPGDALDH1A1POLBHSD11B1 | |
| SCHEMBL26614382 | 0.70 | ALDH1A1 (0.42) | HTTHPGDALDH1A1POLBHSD11B1 | |
| SCHEMBL17560402 | 0.69 | ALDH1A1 (0.38) | HTTHPGDALDH1A1POLBHSD11B1 | |
| SCHEMBL27857071 | 0.69 | ALDH1A1 (0.42) | HTTHPGDALDH1A1POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-107108583-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2020-11-13 | — | — | CN | disclosed |