Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560426 | 0.84 | CHRNB2 (0.47) | HTTPOLBEPHX1EPHX2CA1 | |
| SCHEMBL28498147 | 0.74 | HTT (0.46) | HTTPOLBALDH1A1HPGDEPHX1 | |
| SCHEMBL17560423 | 0.74 | BIRC2 (0.36) | POLBEPHX1CA1CA2 | |
| SCHEMBL4845577 | 0.74 | ALDH1A1 (0.39) | HTTPOLBALDH1A1HPGD | |
| SCHEMBL21066382 | 0.74 | ALDH1A1 (0.39) | HTTPOLBALDH1A1HPGDATM | |
| SCHEMBL4158696 | 0.73 | SIGMAR1 (0.44) | HTTPOLBEPHX1L3MBTL1 | |
| SCHEMBL5201039 | 0.73 | HTT (0.83) | HTTPOLBALDH1A1DPP7MAPK1 | |
| SCHEMBL3946457 | 0.72 | ALDH1A1 (0.42) | HTTPOLBALDH1A1HPGDTHRB | |
| SCHEMBL4725324 | 0.72 | ALDH1A1 (0.42) | HTTPOLBALDH1A1HPGD | |
| SCHEMBL30443406 | 0.71 | ALDH1A1 (0.54) | HTTPOLBALDH1A1HPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016034134-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-03-10 | — | — | WO | disclosed |