Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GRK6 | P43250 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510037 | 0.85 | CNR2 (0.38) | NPSR1PLA2G2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5727065 | 0.69 | GRK6 (0.42) | KDM4EMAPK1NPSR1GRK6ALDH1A1 | |
| SCHEMBL20591086 | 0.69 | TLR8 (0.43) | KDM4EMAPK1NPSR1GRK6ALDH1A1 | |
| SCHEMBL6336697 | 0.67 | TLR8 (0.41) | KDM4EMAPK1NPSR1GRK6ALDH1A1 | |
| SCHEMBL23588215 | 0.67 | NOTUM (0.40) | KDM4EMAPK1NPSR1GRK6ALDH1A1 | |
| SCHEMBL20591096 | 0.67 | TLR8 (0.43) | NPSR1GRK6ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28814096 | 0.66 | GRK6 (0.44) | KDM4EMAPK1NPSR1GRK6PLA2G2A | |
| SCHEMBL28668094 | 0.64 | ALDH1A1 (0.58) | KDM4ENPSR1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8799103 | 0.64 | CYP11B1 (0.49) | KDM4EMAPK1NPSR1GRK6CYP1A2 | |
| SCHEMBL28477692 | 0.64 | ALDH1A1 (0.58) | KDM4ENPSR1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-112135818-A | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-112135818-A | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2020-12-25 | — | — | CN | disclosed |