Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586979 | 1.00 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4940699 | 1.00 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4709438 | 1.00 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL5056855 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4016026 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL23256152 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL1664759 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4198227 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| Hydrochloric Acid SCHEMBL6681663 | 0.91 | OPRM1 (0.50) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL6497247 | 0.89 | F2 (0.57) | OPRM1OPRD1OPRK1F2NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926504-B1 | IN SITU OCCLUDING COMPOSITIONS NCLUDING NATURAL BIODEGRADABLE POLYSACCHARIDES | SURMODICS INC (US) | 2010-01-13 | — | — | EP | disclosed |
| EP-2015794-A2 | HYDROPHILIC SHAPE MEMORY INSERTABLE MEDICAL ARTICLES | SurModics, Inc. (US) | 2009-01-21 | — | — | EP | disclosed |
| US-20080039931-A1 | Hydrophilic shape memory insertable medical articles | SURMODICS, INC. | 2008-02-14 | — | — | US | disclosed |
| WO-2007127318-A2 | HYDROPHILIC SHAPE MEMORY INSERTABLE MEDICAL ARTICLES | SURMODICS, INC. (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070065484-A1 | In situ occlusion using natural biodegradable polysaccharides | SURMODICS MD, LLC | 2007-03-22 | — | — | US | disclosed |
| US-5691311-A | Methods for coating invasive devices with inhibitors of thrombin | BIOGEN, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5514409-A | ANTICOAGULANT PEPTIDES | BIOGEN, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0489070-B1 | NOVEL INHIBITORS OF THROMBIN | BIOGEN INC (US) | 1996-04-24 | — | — | EP | disclosed |
| US-5433940-A | Synthetic molecules mimic action of hirudin by binding to both the low affinity anion-binding exosite and the catalytic site of thrombin | BIOGEN, INC. (US) | 1995-07-18 | — | — | US | disclosed |
| US-5425936-A | Useful for therapeutic, prophylactic and diagnostic purposes | BIOGEN, INC. (US) | 1995-06-20 | — | — | US | disclosed |
| US-5240913-A | Polypeptide anticoagulants | BIOGEN, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| US-5196404-A | Hirudin mimic, polypeptide, hirulog; bivalirudin FDA Orange book listed patent | BIOGEN, INC. (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0529031-A1 | IMPROVED INHIBITORS OF THROMBIN | BIOGEN, INC. (US) | 1993-03-03 | — | — | EP | disclosed |
| WO-1992013952-A1 | IMPROVED INHIBITORS OF THROMBIN | BIOGEN, INC. (US) | 1992-08-20 | — | — | WO | disclosed |
| EP-0489070-A1 | NOVEL INHIBITORS OF THROMBIN. | BIOGEN INC (US) | 1992-06-10 | — | — | EP | disclosed |
| WO-1991002750-A1 | NOVEL INHIBITORS OF THROMBIN | BIOGEN, INC. (US) | 1991-03-07 | — | — | WO | disclosed |
| WO-1990003391-A1 | HIRUDIN PEPTIDES | BIOGEN, INC. (US) | 1990-04-05 | — | — | WO | disclosed |