Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849826 | 1.00 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4940699 | 1.00 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4709438 | 1.00 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL5056855 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4016026 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL23256152 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL1664759 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4198227 | 0.91 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| Hydrochloric Acid SCHEMBL6681663 | 0.91 | OPRM1 (0.50) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL6497247 | 0.89 | F2 (0.57) | OPRM1OPRD1OPRK1F2NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818744-A2 | Process for selecting candidate drug compounds | Proteus Molecular Design Limited (GB) | 1998-01-14 | — | — | EP | disclosed |