Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198227 | 1.00 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL1664759 | 1.00 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL23256152 | 1.00 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL5056855 | 1.00 | OPRM1 (0.51) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| Hydrochloric Acid SCHEMBL6681663 | 0.99 | OPRM1 (0.50) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL6601122 | 0.93 | OPRM1 (0.53) | OPRM1OPRD1NPFFR1NPFFR2 | |
| SCHEMBL4940699 | 0.91 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL8586979 | 0.91 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL2849826 | 0.91 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 | |
| SCHEMBL4709438 | 0.91 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037150-A1 | MASP-2, A Complement Fixing Enzyme, and Uses for It | HELION BIOTECH APS | 2017-02-09 | — | — | US | disclosed |
| US-9441262-B2 | MASP-2, a complement fixing enzyme, and uses for it | HELION BIOTECH APS (DK) | 2016-09-13 | — | — | US | disclosed |
| US-20140134641-A1 | MASP-2, A COMPLEMENT FIXING ENZYME, AND USES FOR IT | HELION BIOTECH APS (DK) | 2014-05-15 | — | — | US | disclosed |
| US-8551790-B2 | MASP 2, a complement-fixing enzyme, and uses for it | HELION BIOTECH APS (DK) | 2013-10-08 | — | — | US | disclosed |
| US-20120219965-A1 | MASP 2, A COMPLEMENT-FIXING ENZYME, AND USES FOR IT | HELION BIOTECH APS (DK) | 2012-08-30 | — | — | US | disclosed |
| US-20090259019-A1 | MASP-2, A COMPLEMENT FIXING ENZYME, AND USES FOR IT | OMEROS CORPORATION (US) | 2009-10-15 | — | — | US | disclosed |
| EP-1303591-B1 | MASP-2, A COMPLEMENT-FIXING ENZYME, AND USES FOR IT | HELION BIOTECH APS (DK) | 2009-06-24 | — | — | EP | disclosed |
| US-20070031420-A1 | MASP-2, a complement-fixing enzyme, and uses for it | HELION BIOTECH APS (DK) | 2007-02-08 | — | — | US | disclosed |
| US-7112414-B2 | Using mannan-binding lectin associated serine protease-2 (MASP-2) for screening enzyme inhibitors which can be used for treatment of infectious and/or inflammatory diseases | OMEROS CORPORATION | 2006-09-26 | — | — | US | disclosed |
| US-7083786-B2 | MASP-2, a complement-fixing enzyme, and uses for it | OMEROS CORPORATION | 2006-08-01 | — | — | US | disclosed |
| US-20040038297-A1 | Masp-2,a complement-fixing enzyme, and uses for it | OMEROS CORPORATION | 2004-02-26 | — | — | US | disclosed |
| CN-1449440-A | MASP-2, a complement fixation enzyme and uses thereof | CHRISTIAN JENSENIUS JENS (DK) | 2003-10-15 | — | — | CN | disclosed |
| US-20030186419-A1 | Masp-3, a complement-fixing enzyme, and uses for it | JENSENIUS JENS CHRISTIAN (DK) | 2003-10-02 | — | — | US | disclosed |
| CN-1433466-A | MASP-3, an enzyme for fixing complement, and uses thereof | JENSENIUS JENS C (DK) | 2003-07-30 | — | — | CN | disclosed |
| EP-1303591-A2 | MASP-2, A COMPLEMENT-FIXING ENZYME, AND USES FOR IT | Jensenius, Jens Christian (DK) | 2003-04-23 | — | — | EP | disclosed |
| EP-1238066-A2 | MASP-3, A COMPLEMENT-FIXING ENZYME, AND USES FOR IT | Jensenius, Jens Christian (DK) | 2002-09-11 | — | — | EP | disclosed |
| US-20020082208-A1 | MASP-2, a complement-fixing enzyme, and uses for it | OMEROS CORPORATION | 2002-06-27 | — | — | US | disclosed |
| US-20020082209-A1 | MASP-2, a complement-fixing enzyme, and uses for it | OMEROS CORPORATION | 2002-06-27 | — | — | US | disclosed |
| WO-2002006460-A2 | MASP-2, A COMPLEMENT-FIXING ENZYME, AND USES FOR IT | JENSENIUS JENS CHRISTIAN (DK) | 2002-01-24 | — | — | WO | disclosed |
| WO-2001040451-A2 | MASP-3, A COMPLEMENT-FIXING ENZYME, AND USES FOR IT | JENSENIUS JENS CHRISTIAN (DK) | 2001-06-07 | — | — | WO | disclosed |