Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 6/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30705299 | 1.00 | TRIM24 (0.43) | TRIM24TRIM33DRD2DRD3DRD1 | |
| SCHEMBL30705318 | 0.88 | TRIM24 (0.43) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL22853919 | 0.88 | TRIM24 (0.43) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL6851157 | 0.87 | TDP1 (0.46) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL3077219 | 0.80 | DRD2 (0.53) | DRD2DRD3DRD1HTR2ADRD4 | |
| SCHEMBL14916013 | 0.78 | TRIM24 (0.38) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL28505304 | 0.77 | ERN1 (0.39) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL28632221 | 0.76 | LMNA (0.36) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL3214016 | 0.76 | ERN1 (0.42) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL21262188 | 0.74 | ERN1 (0.44) | TRIM24TRIM33ERN1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041296-A | Aminoacetamides containing benzo-oxy-alicyclic structure and use thereof | 上海璃道医药科技有限公司 | 2020-12-04 | — | — | CN | disclosed |