Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 9/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30705318 | 0.85 | TRIM24 (0.43) | TRIM24TRIM33ERN1AOC3PIK3CD | |
| SCHEMBL22853919 | 0.85 | TRIM24 (0.43) | TRIM24TRIM33ERN1AOC3PIK3CD | |
| SCHEMBL30705299 | 0.78 | TRIM24 (0.43) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL28501401 | 0.78 | TRIM24 (0.43) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL6852501 | 0.77 | TDP1 (0.46) | TRIM24TRIM33ERN1AOC3MEN1 | |
| SCHEMBL6851157 | 0.68 | TDP1 (0.46) | TRIM24TRIM33ERN1PIK3CDPIK3CA | |
| SCHEMBL28784850 | 0.67 | AOC3 (0.41) | TRIM24TRIM33ERN1AOC3PRKDC | |
| SCHEMBL10430741 | 0.66 | ERN1 (0.44) | TRIM24TRIM33ERN1AOC3KMT2A | |
| SCHEMBL21017668 | 0.66 | ALDH1A1 (0.45) | ERN1AOC3KDM4ENPSR1LMNA | |
| SCHEMBL2265157 | 0.65 | AOC3 (0.44) | AOC3PIK3CAKDM4ENPC1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884041-B2 | Composition for the prevention or treatment of obesity, dyslipidaemia, fatty liver or insulin resistance syndrome, comprising piperonal as an active ingredient | YONSEI UNIVERSITY TECHNOLOGY HOLDINGS, INC. (KR) | 2018-02-06 | — | — | US | disclosed |
| US-20130116315-A1 | COMPOSITION FOR THE PREVENTION OR TREATMENT OF OBESITY, DYSLIPIDAEMIA, FATTY LIVER OR INSULIN RESISTANCE SYNDROME, COMPRISING PIPERONAL AS AN ACTIVE INGREDIENT | NOVA K HEALTH CO., LTD (KR) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116315-A1 | COMPOSITION FOR THE PREVENTION OR TREATMENT OF OBESITY, DYSLIPIDAEMIA, FATTY LIVER OR INSULIN RESISTANCE SYNDROME, COMPRISING PIPERONAL AS AN ACTIVE INGREDIENT | LIPC, PNLIP, CPT1A | TRIM24 2734/4885TRIM33 2049/4885ERN1 4320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.