Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307409 | 0.82 | GALR3 (0.59) | TAAR1ALDH1A1HTTKMT2AGALR3 | |
| SCHEMBL28511396 | 0.81 | KMT2A (0.67) | CRHBPCRHR2ALDH1A1HTTGAA | |
| SCHEMBL28509057 | 0.80 | GALR3 (0.69) | CRHBPCRHR2ALDH1A1HTTGAA | |
| SCHEMBL28220542 | 0.80 | GAA (0.53) | TAAR1HTTGAAGALR3NR2F2 | |
| SCHEMBL28506233 | 0.80 | CRHBP (0.53) | CRHBPCRHR2ALDH1A1HTTGAA | |
| SCHEMBL15094547 | 0.78 | KMT2A (0.62) | HTTKMT2APOLBMEN1KDM4E | |
| SCHEMBL28500108 | 0.78 | ALDH1A1 (0.50) | CRHBPCRHR2ALDH1A1HTTGAA | |
| SCHEMBL28499026 | 0.77 | IGF1R (0.61) | CRHBPCRHR2ALDH1A1HTTGAA | |
| SCHEMBL28501477 | 0.75 | CRHBP (0.50) | CRHBPCRHR2ALDH1A1HTTGAA | |
| SCHEMBL8783600 | 0.74 | ALDH1A1 (0.57) | ALDH1A1HTTKMT2AGALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204010-B | Heterocyclic derivatives and uses thereof | C&C新药研究所 | 2024-03-19 | — | — | CN | claimed |
| CN-112204010-A | Heterocyclic derivatives and use thereof | C&C新药研究所 | 2021-01-08 | — | — | CN | claimed |
| CN-112204010-B | Heterocyclic derivatives and uses thereof | C&C新药研究所 | 2024-03-19 | — | — | CN | disclosed |
| CN-112204010-A | Heterocyclic derivatives and use thereof | C&C新药研究所 | 2021-01-08 | — | — | CN | disclosed |